CUSTOM ITEM: HPLC Column, Bidentate C8 2.o, 2.2um, 2.1mm ID x 100mm Length, 120A. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40208‑10P‑3 Cogent Bidentate C8™ 2.o HPLC Column is a custom‑manufactured, high‑efficiency reversed‑phase column designed for analytical separations where C18 chemistry is overly retentive and alternative selectivity is required. Built on Cogent TYPE‑C™ silica hydride technology, this column delivers excellent selectivity, faster equilibration, and near‑UHPLC performance on standard HPLC systems.
The Bidentate C8™ 2.o stationary phase uses a shorter alkyl ligand compared to C18 while retaining the chemical robustness of direct silicon–carbon bonding. This makes the column particularly effective for hydrophobic and non‑polar compounds that are difficult to retain in aqueous mobile phases, yet are excessively retained on C18 columns.
The 2.1 mm internal diameter supports lower flow rates and reduced solvent consumption, while the 100 mm length provides increased plate count and resolving power compared with 50 mm formats. Notably, this configuration can deliver run times similar to 4.6 mm ID columns, but with significantly reduced mobile‑phase usage—without requiring specialized low‑flow equipment beyond standard, well‑controlled analytical HPLC systems.
Why Choose the 2.1 × 100 mm Bidentate C8™ 2.o Format
This format is commonly selected when:
C18 columns provide excessive retention or long run times
Hydrophobic or non‑polar analytes require controlled retention
Increased resolution is needed beyond short LC‑MS columns
Solvent‑use reduction is desired without changing instrumentation
The 100 mm length increases separation efficiency, while TYPE‑C™ silica hydride chemistry maintains fast equilibration and long column life across a broad method window.
Key Features
Cogent TYPE‑C™ Silica Hydride Technology
Reduced silanol activity and secondary interactions
Faster equilibration than conventional silica‑based C8 columns
Excellent chemical stability and reproducibility
Bidentate C8™ 2.o Bonding
Two‑point attachment via direct Si–C bonds
Alternative selectivity where C18 is too retentive
Controlled hydrophobic retention for challenging analytes
Near‑UHPLC Efficiency (2.2 µm)
High efficiency on standard HPLC systems
Improved resolution and peak capacity
Suitable for demanding analytical workflows
Solvent‑Efficient Analytical Geometry
2.1 mm ID × 100 mm length
Lower flow rates reduce solvent use
Comparable run times to larger‑ID analytical columns
Typical Applications
Analytical HPLC requiring alternative reversed‑phase selectivity
Hydrophobic and non‑polar compounds
Situations where C18 retention is excessive
High‑resolution method development
Solvent‑reduction initiatives
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable